• María Del Mar Sánchez-Fernández, Gustavo A Reyes Del Paso, Pedro L Quirós-Ganga, Antonio S Moreno-Salazar, and María José Fernández-Serrano.
• Departamento de Psicología, Universidad de Jaén, Jaén, España. Electronic address: mmsanche@ujaen.es.
• Med Clin (Barc). 2024 Feb 23; 162 (4): 147156147-156.

BackgroundPatients with chronic kidney disease on hemodialysis (HD) often have cognitive deficits. However, there are few studies that have examined the neuropsychological impairments of patients receiving peritoneal dialysis (PD).MethodsExecutive functions, processing speed and verbal memory were assessed in 27 PD patients, 42 HD patients, and 42 healthy participants (HP). Systolic blood pressure and total time on renal replacement therapy (RRT) were controlled statistically. Associations between performance and clinical factors were analyzed using correlations and multiple regression.ResultsThe DP group showed better performance compared to the HD group in verbal fluency, working memory, cognitive flexibility, planning and decision making. The DP group showed worse execution than the HP group in verbal inhibition and memory. Executive function scores were positively associated with total months on PD, total months on RRT, total months on HD, albumin, total cholesterol, and phosphorus, and negatively with ferritin.ConclusionGlobal executive functioning was more optimal in PD patients than in HD patients. The results show the positive effect of PD on executive functions, which must be taken into account when choosing the TRS. The associations observed between biochemical factors and performance show the importance of maintaining an adequate nutritional status in these patients.Copyright © 2023 Elsevier España, S.L.U. All rights reserved.

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