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- Shigehisa Kajikawa, Satsuki Murakami, Akiyoshi Takami, Akira Satou, Toyonori Tsuzuki, Tomoyuki Ogisu, Toshiyuki Yonezawa, Hiroyuki Tanaka, Akihito Kubo, and Satoru Ito.
- Department of Respiratory Medicine and Allergology, Aichi Medical University, Japan.
- Intern. Med. 2024 Jul 15; 63 (14): 206320672063-2067.
AbstractA 29-year-old woman who had been diagnosed with acute myeloid leukemia presented with persistent grade-4 febrile neutropenia (FN) after initial chemotherapy with idarubicin and cytarabine. Despite intensive treatment, FN persisted. Subsequently, her nose became reddish and swollen, obstructing the nasal cavities. Computed tomography revealed swelling of the nostrils and an irregular tracheal surface. Debridement of the nasal lesion and a bronchoscopic biopsy of the tracheal lesion were also performed. A histopathological examination revealed pseudocarcinomatous hyperplasia (PCH) of the nose and necrotizing tracheitis. Both nasal PCH and necrotizing tracheitis ameliorated when the patient recovered from leukocytopenia.
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