• Internal medicine · Jul 2024

    Case Reports

    A Case of Successful Pregnancy and Delivery in a Chronic Renal Failure Patient with Membranoproliferative Glomerulonephritis and Preeclampsia-related Nephrotic Syndrome.

    • Kumi Nakai, Koji Sato, Nao Nohara, Miyuki Takagi, Masao Kihara, Seiji Ueda, Tomohito Gohda, and Yusuke Suzuki.
    • Department of Nephrology, Juntendo University Faculty of Medicine, Japan.
    • Intern. Med. 2024 Jul 15; 63 (14): 203520422035-2042.

    AbstractA 37-year-old woman with chronic kidney disease (CKD) stage G4 with membranoproliferative glomerulonephritis was hospitalized for nephrotic syndrome and hypertension due to superimposed preeclampsia at 27 weeks into her third pregnancy. Proteinuria did not worsen significantly after pulse steroid therapy. Delivery was induced at 30 weeks' gestation due to the maternal renal function and fetal growth. No obvious fetal complications other than preterm delivery were observed. In this case, we successfully managed a high-risk patient with membranoproliferative glomerulonephritis complicated by advanced CKD, nephrotic syndrome, and hypertension, which are independent risk factors for pregnancy complications.

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