• Vittorio Semeraro, Vitanio Palmisano, Nicola Limbucci, Simone Comelli, Chiara Comelli, Maria Porzia Ganimede, Emilio Lozupone, Michele Barone, Antonio Marrazzo, Andrea Paladini, Giuseppina Della Malva, Briatico VangosaAlessandraA0000-0002-4099-0825Radiology and Neuroradiology Unit, "SS. Annunziata" Hospital, Taranto, Italy., Antonio Laiso, Leonardo Renieri, Francesco Capasso, Roberto Gandini, Carmine Di Stasi, Maurizio Resta, Salvatore Mangiafico, and Nicola Burdi.
• Radiology and Neuroradiology Unit, "SS. Annunziata" Hospital, Taranto, Italy.
• Neurosurgery. 2023 Dec 1.

Background And ObjectivesThis multicenter study aimed to assess the safety and efficacy of the Woven EndoBridge (WEB) device for treating unruptured wide-neck intracranial bifurcation aneurysms (WIBAs) with short-, mid-, and long-term follow-ups (FUPs).MethodsConsecutive patients with unruptured WIBAs treated with WEB between December 2014 and January 2018 were included. Patient, aneurysm, and device characteristics were collected and analyzed retrospectively. Morbidity and mortality rates were determined by collecting intraprocedural, periprocedural, and delayed complications. Aneurysm occlusion was assessed at 1, 3, and 5 years using a 3-grade scale: complete occlusion, neck remnant, and residual aneurysm. Complete occlusion and neck remnant were considered as adequate occlusion. Patients who received re-treatment were also evaluated.ResultsThe study included 104 consecutive patients (55.8% female, mean age 58.6 ± 11.8 years). Aneurysm maximum size, neck, and dome-to-neck mean were, respectively, 6.9 ± 2.1 mm, 4.5 ± 1.2 mm, and 1.4 ± 0.3 mm. One-year FUP was collected for 95 patients, and 3- and 5-year FUPs were collected for 83 patients. Adequate occlusion was observed at 1-year FUP in 90.5% (86/95), 91.6% (76/83) was observed at 3-year FUP, and 92.8% (77/83) at 5-year FUP. None of the aneurysms bled after treatment. During FUP, 6/83 patients (7.2%) were re-treated for residual aneurysm. Morbidity and mortality rates closely related to aneurysm occlusion were 0% (0/104).ConclusionThe WEB device was safe and effective for treating unruptured WIBAs, both in short-term and long-term FUPs.Copyright © Congress of Neurological Surgeons 2023. All rights reserved.

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