• Medicine · Dec 2023

    Review Case Reports

    Perianal rhabdomyosarcoma in an adult: A case report and review of the literature.

    • Ning Yang, Dexian Kong, Xv Wang, and Yabin Liu.
    • Department of General Surgery, The First Affiliated Hospital, Hebei Medical University, Shijiazhuang, China.
    • Medicine (Baltimore). 2023 Dec 1; 102 (48): e36276e36276.

    AbstractPerianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles. After 3 cycles of nivolumab, dacarbazine, cisplatin, and vinblastine therapy, a partial response was identified in the patient. The surgical resection was performed. The patient received neoadjuvant chemotherapy before surgery and was weak after surgery, so he did not receive chemoradiotherapy. The patient succumbed after 11 months postoperatively due to widespread intraabdominal metastasis.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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