• J. Cardiothorac. Vasc. Anesth. · Mar 2024

    Review Case Reports

    How Would We Treat Our Own Cystic Fibrosis With Lung Transplantation?

    • von DossowVeraVInstitute of Anesthesiology and Pain Therapy, Heart and Diabetes Center Bad Oeynhausen, University Clinic of Ruhr-University Bochum, Bochum, Germany., Nikolai Hulde, Henning Starke, and Rene Schramm.
    • Institute of Anesthesiology and Pain Therapy, Heart and Diabetes Center Bad Oeynhausen, University Clinic of Ruhr-University Bochum, Bochum, Germany.
    • J. Cardiothorac. Vasc. Anesth. 2024 Mar 1; 38 (3): 626634626-634.

    AbstractLung transplantation is the only therapy for patients with end-stage lung disease. In advanced lung diseases such as cystic fibrosis (CF), life expectancy increases, and it is important to recognize extrapulmonary comorbidities. Cardiovascular involvement, including pulmonary hypertension, right-heart failure, and myocardial dysfunction, are manifest in the late stages of CF disease. Besides right-heart failure, left-heart dysfunction seems to be underestimated. Therefore, an optimal anesthesia and surgical management risk evaluation in this high-risk patient population is mandatory, especially concerning the perioperative use of mechanical circulatory support. The use of an index case of an older patient with the diagnosis of cystic fibrosis demonstrates the importance of early risk stratification and strategy planning in a multidisciplinary team approach to guarantee successful lung transplantation.Copyright © 2023 Elsevier Inc. All rights reserved.

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