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- Goce Dimeski and Peter S Kruger.
- Chemical Pathology, Princess Alexandra Hospital, Queensland Health Pathology, Brisbane, QLD, Australia.
- Crit Care Resusc. 2021 Jun 1; 23 (2): 141143141-143.
AbstractSerum creatinine and total protein are routinely measured biochemical parameters used in clinical medicine. An abnormal result caused by interference with the assay does not accurately reflect a patient's clinical state and therefore risks misleading clinicians. We report the case of a patient who had unexplainable high creatinine and total protein results. The blood collection was contaminated with intravenous fluid and the patient was receiving piperacillin/tazobactam. Additional laboratory studies demonstrated piperacillin/tazobactam was the cause of the false positive results and the elevation in both serum creatinine and protein level was dependent on the concentration of antibiotic present.© 2021 College of Intensive Care Medicine of Australia and New Zealand.
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