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- Hidekazu Azumi, Masayuki Kubo, Atsushi Otani, Shinichi Ochi, Shinya Kobayashi, Yasumasa Miyataka, Fumihiko Nakamura, and Hideo Yagi.
- Department of Hematology and Oncology, Nara Prefecture General Medical Center, Japan.
- Intern. Med. 2024 Jul 15; 63 (14): 206920762069-2076.
AbstractA 63-year-old woman with adult T-cell leukemia (ATL) lymphomatous type developed a mild dry cough. Computed tomography revealed lung lesions with a tree-in-bud appearance during intensive chemotherapy. Antibodies against Mycobacterium avium complex were positive. Bronchoalveolar lavage culture showed growth of M. abscessus complex. Finally, M. abscessus subsp. massiliense was also identified. Sequential use of antimicrobials, including macrolides, was introduced during intensive chemotherapy, and the patient successfully underwent allogeneic hematopoietic stem cell transplantation (AHSCT). This is the first case report of a patient with ATL complicated by M. massiliense lung infection, who was successfully treated with haploidentical AHSCT using various combinations of antimicrobials.
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