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Dtsch. Med. Wochenschr. · Mar 1986
[HTLV-III in persons with intravenous drug abuse. Correlation of antibodies against HTLV-III with neopterin and TH/TS].
- P Hengster, H G Blecha, F Deinhardt, V Erfle, D Fuchs, F D Goebel, L G Gürtler, A Hausen, H Hinterhuber, and G Reibnegger.
- Dtsch. Med. Wochenschr. 1986 Mar 21; 111 (12): 453457453-7.
AbstractAntibodies against HTLV-III, neopterin levels in blood and urine, TH/TS ratio and hepatitis marker were determined in 34 clinically symptom-free persons known to be intravenous drug abusers. 15 persons were positive in the ELISA and Western-blot tests. There was a strong reaction to protein p24 compared with that to protein p41. In 12 of 14 persons who were antibody-positive the neopterin level in morning urine was elevated; an abnormal TH/TS ratio was present in nine of 13 persons. In future, determination of neopterin and of antibodies against certain proteins of HTLV-III may make it possible to provide a simple way of prognosticating on the course of an HTLV-III infection.
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