• A&A practice · Dec 2023

    Case Reports

    Acute Dystonic Reaction After Propofol Administration: A Pediatric Case Report.

    • Lucy Zhao, Mary Ellen McCann, Raymond Seungjoon Park, Danielle Bennett Pier, and Dusica Bajic.
    • From the Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
    • A A Pract. 2023 Dec 1; 17 (12): e01732e01732.

    AbstractWe present a case of a 12-year-old female with a history of infantile spasms who developed a propofol-associated acute dystonic reaction after emergence from general anesthesia for foot surgery. Uniquely, the patient's postoperative symptoms of an acute dystonic reaction were refractory to standard treatment with anticholinergics but were successfully treated with corticosteroids. The absence of any dystonic symptoms following subsequent foot surgery under general anesthesia without propofol supported a propofol-associated etiology. This case may contribute to a better understanding of the underlying mechanisms of propofol-associated acute dystonic reactions and adds a possible new treatment option.Copyright © 2023 International Anesthesia Research Society.

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