• Revista clínica española · Dec 2020

    Neutrophils as instigators of thrombosis: Beyond antimicrobial protection.

    • J A Páramo.
    • Servicio de Hematología, CUN. Laboratorio Aterotrombosis, CIMA. Universidad de Navarra, IdiSNA, CIBERCV, Pamplona, España. Electronic address: japaramo@unav.es.
    • Rev Clin Esp. 2020 Dec 1; 220 (9): 583586583-586.

    AbstractWhen activated, neutrophils release structures (NETs) composed of DNA, histones and granular proteins that provide an ideal matrix for platelet activation and coagulation mechanisms, thereby contributing to the pathogenesis of thrombosis in venous and arterial territories, as well as cancer-associated thrombosis. NETs play a key role in immunothrombosis, a term that describes the relationship between the immune response and coagulation.Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

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