• Muhammad Fadil, Eryati Darwin, Hirowati Ali, Doni Firman, Muzakkir Amir, and Andriany Qanitha.
• Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Andalas, Central General Hospital "Dr. M. Djamil", Padang.
• Gac Med Mex. 2023 Jan 1; 159 (5): 421425421-425.

BackgroundIschemic conditioning may help patients with ST-segment elevation myocardial infarction (STEMI) to limit ventricular remodeling.ObjectivesTo investigate the effect of remote ischemic postconditioning (RIPC) on left ventricular function during primary percutaneous coronary intervention (PPCI) in patients with STEMI.Material And MethodsPre- and post-test intervention study with a total of 60 STEMI patients. Patients were divided in two groups: with and without RIPC.ResultsDuring the 6-month follow-up, a significant difference in left ventricular ejection fraction was observed in patients who underwent PPCI, which was higher in the group with RIPC in comparison with the group without RIPC: 1.0% (-1.0 to 4.3) vs. -1.0% (-4.0 to 1.3), p = 0.033. In addition, at 6-month measurement, left ventricular end-systolic volume in patients without RIPC was higher in comparison with their counterparts: 79.3 ± 30.5 mL vs. 64.4 ± 21.4 mL, p = 0.032.ConclusionsRIPC shows favorable effects on left ventricular function and, therefore, in the future, it could be a potential cardioprotective strategy against ischemia-reperfusion injury in STEMI patients.Copyright: © 2023 Permanyer.

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