• Kenji NawaRicardoR0000-0002-0852-7013Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Luiz Ferreira De CamillisMarcioM0000-0001-5566-6422Hospital Moinhos de Vento, Porto Alegre, RS, Brazil., Monique Buttignol, Machado KutchakFernandaF0000-0002-5717-0380Universidade Vale dos Sinos, Porto Alegre, RS, Brazil.Universidade Federal do Rio Grande do Sul, Postgraduate Program in Health Sciences: Cardiology and Cardiovascular Sciences, Porto Alegre, RS, Brazil., Eder Chaves Pacheco, Louise Helena Rodrigues Gonçalves, Leonardo Miguel Correa Garcia, Tavares TimenetskyKarinaK0000-0002-4176-2445Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., and Luiz Alberto Forgiarini.
• Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
• Colomb Medica. 2023 Jul 1; 54 (3): e2005580e2005580.

BackgroundThe use of instruments in clinical practice with measurement properties tested is highly recommended, in order to provide adequate assessment and measurement of outcomes.ObjectiveTo calculate the minimum clinically important difference (MCID) and responsiveness of the Perme Intensive Care Unit Mobility Score (Perme Score).MethodsThis retrospective, multicentric study investigated the clinimetric properties of MCID, estimated by constructing the Receiver Operating Characteristic (ROC). Maximizing sensitivity and specificity by Youden's, the ROC curve calibration was performed by the Hosmer and Lemeshow goodness-of-fit test. Additionally, we established the responsiveness, floor and ceiling effects, internal consistency, and predictive validity of the Perme Score.ResultsA total of 1.200 adult patients records from four mixed general intensive care units (ICUs) were included. To analyze which difference clinically reflects a relevant evolution we calculated the area under the curve (AUC) of 0.96 (95% CI: 0.95-0.98), and the optimal cut-off value of 7.0 points was established. No substantial floor (8.8%) or ceiling effects (4.9%) were observed at ICU discharge. However, a moderate floor effect was observed at ICU admission (19.3%), in contrast to a very low incidence of ceiling effect (0.6%). The Perme Score at ICU admission was associated with hospital mortality, OR 0.86 (95% CI: 0.82-0.91), and the predictive validity for ICU stay presented a mean ratio of 0.97 (95% CI: 0.96-0.98).ConclusionOur findings support the establishment of the minimum clinically important difference and responsiveness of the Perme Score as a measure of mobility status in the ICU.Copyright © 2023 Colombia Medica.

12 keywords...

hide…