• Internal medicine · Aug 2024

    Case Reports

    A Case of Overlap of Chronic Pulmonary Aspergillosis on Allergic Bronchopulmonary Aspergillosis.

    • Takashi Ishiguro, Taisuke Isono, Tomoya Maruyama, Miyuki Ueda, Yoshihiko Shimizu, and Yotaro Takaku.
    • Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan.
    • Intern. Med. 2024 Aug 1; 63 (15): 216721712167-2171.

    AbstractAn 80-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) was admitted to our institution in 2023 for an enlarged pulmonary mass lesion. She had developed ABPA in 2017, and corticosteroid therapy had improved the mucoid impaction of the bronchi. Because part of the lesion remained, increased doses of corticosteroid, antifungals, and biologics were administered, but the pulmonary lesion enlarged in 2022. Bronchoscopy showed necrotic tissue in the bronchial lumen, and bronchial washing fluid showed neutrophilic inflammation and fungal hyphae. We subsequently diagnosed her as having chronic pulmonary aspergillosis overlapping ABPA, and voriconazole was started that resulted in shrinkage of the nodules.

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