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Comparative Study
Determination of the PCO2-dependent component of the H+ concentration in venous and arterial blood plasma.
- M Mochizuki.
- Geriatric Respiratory Research Center, Nishimaruyama Hospital, Sapporo, Japan.
- Adv Exp Med Biol. 1997 Jan 1;411:55-64.
AbstractIn normal venous blood plasma, the regression line of [H+] plotted against the PCO2 was linear against the square root of PCO2. Sequential measurements in venous and arterial blood of PCO2 and [H+] showed that the venous-arterial (V-A) difference in [H+] was linearly related to the V-A difference in the square root of PCO2, the regression line having the same slope as that of the venous [H+] plotted against the square root of PCO2. These findings suggested that the venous [H+] on the regression line represents the PCO2-dependent component, of [H+], [H+]*. The PCO2-independent component, delta [H+], can then be given by subtracting [H+]* from the measured [H+]. The delta [H+] in venous blood agreed well with that in arterial blood with a correlation coefficient of 0.99, supporting the validity of the value of [H+]*.
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