• Der Anaesthesist · Apr 2007

    Review

    [Hypertonic saline solution for reduction of intracranial pressure. Are there doubts?].

    • H Theilen, M Ragaller, and T Koch.
    • Klinik und Poliklinik für Anästhesie und Intensivtherapie, Universitätsklinik Carl Gustav Carus der Technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden. Hermann.Theilen@uniklinikum-dresden.de
    • Anaesthesist. 2007 Apr 1;56(4):385-7.

    AbstractOsmotherapy, i.e. the intravenous administration of hyperosmolar solutions, is one of the mainstays of therapy for reduction of a pathologically increased intracranial pressure, in addition to analgosedation and raising the upper body of the patient. The administration of mannitol as a osmotherapeutic agent is, however, marred by considerable side-effects. A possible alternative is the use of hypertonic saline solution (NaCl). The advantages and disadvantages of this option are considered as well as points still in question.

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