• Medicine · Dec 2023

    Clinical characteristics of perioperative central fever and its relationship with anesthesia.

    • Bo Sun, Mingfeng He, Yajun Huang, and Jindi Jiang.
    • Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital), Nanjing, Jiangsu Province, China.
    • Medicine (Baltimore). 2023 Dec 15; 102 (50): e36523e36523.

    AbstractTo analyze clinical characteristics and anesthesia-related factors influencing central fever during cranial neurosurgery. 31 central fever cases (observation) and 120 controls (no fever) underwent detailed investigation. Anaesthesia-related variables were analyzed using logistic regression. Observation group exhibited significantly elevated indicators-CSF white blood cells, protein, CRP, severe EEG abnormalities, abnormal imaging, positive meningeal signs, seizures, consciousness disorders, and status epilepticus (P < .05). Anesthesia plans showed no influence (P > .05). pH, PaCO2, PaO2, SaO2, MAP, ICP, CPP, and SjiO2 didn't impact central fever (P > .05). However, high HR, low Da-jvO2, and low CEO2 were independent risk factors (P < .05). Central fever, marked by CNS abnormalities, manifests with distinctive clinical features. Anesthesia plans have limited impact, while elevated HR, low Da-jvO2, and low CEO2 independently contribute to central fever. Understanding these factors is crucial for perioperative care optimization.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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