• O V Blagova, I N Alieva, V A Kulikova, A V Nedostup, E A Kogan, V P Sedov, D A Parfenov, A N Volovchenko, and N D Sarkisova.
• Sechenov First Moscow State Medical University (Sechenov University).
• Terapevt Arkh. 2023 May 31; 95 (4): 327334327-334.

AbstractDiagnosis and treatment of myocarditis can be challenging, including determining indications for heart transplantation. We present a 6-year medical history of a 54 years old patient with severe morphologically verified viral-negative lymphocytic myocarditis and systemic manifestations (onset of hemorrhagic vasculitis) combined with moderate coronary atherosclerosis, which regressed according to repeated coronary angiography. For 5 years, the patient received immunosuppressive therapy with methylprednisolone and azathioprine with a significant improvement. Repeated relapses of atrial fibrillation required correction of basic therapy and plasmapheresis. The disease was complicated by thyrotoxicosis and multi-organ dysfunction; the autopsy showed persistent myocarditis activity. The myocarditis is a chronic condition and requires a review of the treatment strategy at each stage.

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