• Internal medicine · Aug 2024

    Case Reports

    Transient Sinus Node Dysfunction Associated with Herpes Simplex Encephalitis.

    • Ryusuke Sekii, Tomoaki Shimizu, and Kiyoshi Hibi.
    • Department of Cardiology, Kanagawa Prefectural Ashigarakami Hospital, Japan.
    • Intern. Med. 2024 Aug 1; 63 (15): 214321472143-2147.

    AbstractSinus arrest and inappropriate sinus bradycardia are sinus node dysfunction (SND), which cause loss of consciousness. Cardiac pacing is recommended in patients with symptoms, such as syncope or dizziness. Several conditions can induce these arrhythmias; however, whether or not intracranial infectious diseases, such as herpes simplex encephalitis (HSE), can cause secondary SND is unclear. We encountered a patient with sinus arrest and transient sinus bradycardia associated with HSE. Since cardiac pause was never monitored and the bradycardia improved after HSE treatment, HSE was suspected to be the cause of SND. Although the underlying mechanisms have not yet been completely elucidated, HSE may cause secondary SND.

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