• Eli Y Adashi, Daniel P O'Mahony, and David S Guzick.
• From the Professor of Medical Science, Brown University, Providence, RI (EYA); Brown University Library, Providence, RI (DPO); University of Rochester School of Medicine and Dentistry, Rochester, NY (DSG); UF Health, University of Florida, Gainesville FL (DSG). eli_adashi@brown.edu.
• J Am Board Fam Med. 2024 Jan 5; 36 (6): 106510671065-1067.

AbstractThe high cost of prescription drugs in the U.S. remains an ongoing national challenge. A recurring focal point in discussions over this distressing steady state is the role(s) played by Pharmacy Benefit Managers (PBMs) who negotiate drug prices with pharmaceutical manufacturers, conduct drug utilization reviews, engage in disease management, and see to formulary creation. At their inception, the multiple newly established PBMs were arguably intent on constraining the rise of prescription drug prices. At the time of this writing, however, the lion share of a far less competitive PBM market is controlled by CVS Caremark, Express Scripts, and OptumRx. It is this evolving reality which could be interpreted to mean that the PBMs may have become part of the problem, rather than part of the solution. Expanded scrutiny of the PBMs by Federal and State authorities as well as by Professional Medical Associations must not be delayed with an eye toward affording the public with relief from the high cost of prescription drugs.© Copyright by the American Board of Family Medicine.

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