• Junwei Duan, Xiaoyan Wang, Chenxi Xu, and Rongxin Guo.
• Changchun University of Chinese Medicine Changchun, Changchun, Jilin, China.
• Medicine (Baltimore). 2024 Jan 5; 103 (1): e36737e36737.

RationaleBrunner gland adenoma (BGA) is a rare benign duodenal tumor that is an adenomatoid lesion in nature rather than an actual tumor. Patients with different adenoma sizes have various clinical manifestations with nonspecific clinical symptoms. Here, We report a case of BGA with black stool and anemia as the primary manifestations.Patient ConcernsA young female patient was admitted to the hospital because of black stool and anemia. Endoscopic surgery was performed to a definitive diagnosis, and endoscopic tumor-like lesions were resected.DiagnosisThe patient was diagnosed with duodenal Brunner adenoma and received related treatment.OutcomesAfter treatment, the patient symptoms improved, and he was discharged.LessonsBrunner adenoma of the duodenum is a rare benign duodenum tumor. This report paper describes a case of BGA with black stool and anemia as the primary manifestations, followed by endoscopic resection and treatment. The literature on Brunner adenoma of the duodenum has been analyzed and discussed. Clinicians should pay attention to differentiating the disease based on atypical symptoms.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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