• Disease-a-month : DM · Jan 2024

    Review

    Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management.

    • Zara Manuelyan, Edward Butt, and Sreeram Parupudi.
    • Department of Internal Medicine, Division of Gastroenterology and Hepatology, The University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
    • Dis Mon. 2024 Jan 1; 70 (1S): 101674101674.

    AbstractBehçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from gastroenterology viewpoint.Copyright © 2023. Published by Elsevier Inc.

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