• S. Afr. Med. J. · Dec 1990

    Randomized Controlled Trial Comparative Study Clinical Trial

    Synthetic laminaria tent for cervical ripening.

    • J S Bagratee and J Moodley.
    • Department of Obstetrics and Gynaecology, University of Natal, Durban.
    • S. Afr. Med. J. 1990 Dec 15; 78 (12): 738741738-41.

    AbstractThe efficacy and safety of a synthetic laminaria tent (Lamicel; Cabot) in ripening the cervix before induction of labour was compared with prostaglandin E2 (PGE2) oral tablets used intravaginally. Eighty patients were randomly assigned to use of the laminaria tent (N = 40) or PGE2 (N = 40). There were an equal number of primigravidas and multigravidas in each group. The only significant difference between the groups was the higher frequency of uterine hypertonicity (29 v. 5 : PGE2 v. tent) and consequent fetal distress (5 v. 1 : PGE2 v. tent) in the PGE2 group. However, the duration of labour was shorter in the PGE2 group than in the tent group (10, 14 h v. 11,61 h). These findings indicate that the synthetic laminaria tent is the preferred agent for cervical ripening in high-risk pregnancies and in developing countries.

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