• Yae Ji Choi, Yeon Hee Hong, Haerin Paik, Seul Ki Kim, Jung Ryeol Lee, and Chang Suk Suh.
• Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
• J. Korean Med. Sci. 2024 Jan 8; 39 (1): e14e14.

AbstractThis article reports the live birth of a healthy newborn using vitrified-warmed oocytes from fertility preservation before ovarian surgery. The patient in our case underwent two cycles of controlled ovarian stimulation before laparoscopic bilateral ovarian cystectomy for endometriosis, and a total of 23 mature oocytes were vitrified. After surgery, her pathologic reports revealed a serous borderline tumor and endometrioma. Fifteen months after her second surgery of laparoscopic right salpingo-oophorectomy and left ovarian cystectomy owing to recurrence, she had been married by then, and three of the frozen oocytes were thawed for intracytoplasmic sperm injection. These oocytes were cryopreserved for 2.5 years. All three were fertilized, and two grade-A cleavage-stage embryos were transferred. A singleton pregnancy was achieved, resulting in the delivery of a healthy baby boy at 39.3 weeks of gestation. Oocyte cryopreservation is an effective method for fertility preservation prior to ovarian surgery when ovarian function decline is predictable.© 2024 The Korean Academy of Medical Sciences.

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