• World Neurosurg · Mar 2024

    A Study on the Efficacy and Safety of Pipeline Shield Stents and Non-Modified Surface Flow-Diverting Stents in patients with Intracranial Aneurysms.

    • Julio García-Núñez, D VeraDanielaDInterventional Radiology Department, Fundación Oftalmológica de Santander - Clínica Ardila Lülle, Floridablanca, Colombia. Electronic address: ddveracamargo@gmail.com., Andrés F Ortiz, Adriana Rodríguez, Juan José Lara, María José Gomez, Sergio Serrano-Gómez, Adriana Reyes, Carlos Ferreira-Prada, Melquizidel Galvis-Méndez, Oliverio Vargas-Pérez, and Daniel E Mantilla-García.
    • Interventional Radiology Department, Fundación Oftalmológica de Santander - Clínica Ardila Lülle, Floridablanca, Colombia; Interventional Radiology Department, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.
    • World Neurosurg. 2024 Mar 1; 183: e781e786e781-e786.

    BackgroundFew studies have compared the Pipeline Shield stents with previous generations of flow-diverting stents (FDSs) for the treatment of unruptured intracranial aneurysms. This study aimed to evaluate the efficacy and safety of Pipeline Shield stents and FDSs without modified surfaces.MethodsThe present evaluation is a retrospective cohort study of patients endovascularly treated with Pipeline Shield stents or FDSs without modified surfaces for unruptured intracranial aneurysms between January 2014 and June 2022. The data analyzed were obtained from the anonymized database of our institution's interventional radiology service.ResultsA total of 147 patients with 155 unruptured intracranial aneurysms were included. Of the 155 aneurysms, 96 were treated with Pipeline Shield stents and 59 with FDSs without modified surfaces. The aneurysms treated with Pipeline Shield stents had higher 6-month (O'Kelly-Marotta [OKM] D; 87.5% vs. 71.4%; P = 0.025) and 1-year (OKM D; 82.5% vs. 63.0%; P = 0.047) occlusion rates than the aneurysms treated using FDSs without modified surfaces. No differences between the devices were found at the 1-year follow-up in the incidence of ischemic stroke (P = 0.939) or hemorrhagic complications (P = 0.559).ConclusionsPipeline Shield stents demonstrated superior complete occlusion rates (OKM D) at both the 6-month and the 1-year follow-up assessments compared with nonmodified surface FDSs. No significant differences were found in the safety profiles between the 2 types of stents with regard to thromboembolic complications and ischemic events. Further research with larger study populations is necessary to validate these findings.Copyright © 2024 Elsevier Inc. All rights reserved.

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