• Xiaoyu Ma, Cheng Zhang, Yunxia Wang, Kunyao Yu, Zhe Jin, Chunbo Zhang, Jing Ma, Jiping Liao, and Guangfa Wang.
• Department of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing, China.
• Postgrad Med. 2024 Jan 1; 136 (1): 303530-35.

ObjectivesMorning dry mouth, commonly seen in Obstructive Sleep Apnea (OSA) patients, is absent in current OSA screening tools. This study evaluated the link between morning dry mouth and OSA's clinical symptoms and complications, aiming to determine its viability as a screening indicator.MethodsThis research analyses baseline data from a prospective cohort study (the PIFCOPD study). Demographic information, medical history, and the presence of morning dry mouth symptoms were collected. The STOP-Bang questionnaire was performed for OSA screening. Logistic regression analyses were employed to establish the correlations between morning dry mouth and the clinical symptoms and comorbidities of OSA.Result1291 participants (62.1±7.5 years; 501 males, 790 females) were included, of which 416 reported morning dry mouth (32.2%). 42.6% in the high-risk OSA group and 22.1% in the low-risk group reported morning dry mouth. Individuals with morning dry mouth also showed higher STOP-Bang scores (3.3±1.6 vs. 2.3±1.4, P<0.01). Significant associations were found between morning dry mouth and loud snoring, observed sleep apnea, daytime fatigue, and hyperlipidemia (P<0.01), but not with alcohol consumption, tea consumption, diabetes, or hypertension.ConclusionMorning dry mouth is associated with increased OSA risk and its clinical signs, suggesting its potential as an OSA screening symptom.Clinical Trial RegistrationThis study has been registered at www.ClinicalTrials.gov (registration identifier: NCT03532893) on 21 May 2018.

19 keywords...

hide…