• Samson O Onemu, Emmanuel Ifeanyi Obeagu, Adeniyi Adewumi Popoola, Michael A Osuntuyi, and Clement N Isibor.
• Department of Medical Laboratory Science, Achievers University, Owo, Nigeria.
• Medicine (Baltimore). 2024 Jan 12; 103 (2): e36969e36969.

AbstractStone quarry activities in Nigeria are mostly unregulated such that the workers in these quarries are continuously exposed to the inhalation of silica dust. It has been observed that silica dust particles negatively impact the health of stone quarry workers which usually manifest as respiratory difficulties, asthma-like illnesses and other adventitious events of the lungs. The study was designed to evaluate the probable immunological impact of silica dust inhalation from stone crushing by workers. Blood samples were collected from consenting workers and analyzed for total white blood cells and their subsets. Absolute CD4 cells numbers were also determined. The results indicated that neutrophils and eosinophils numbers increased significantly (P < .05) and CD4 counts declined significantly (P < .001). Alteration in these proportions is a pointer to the injurious impact of silica dust on the immune system of these workers. The findings in this study should spur actions in the education of these workers on the need for the use of proper personal protection equipment and the establishment of a scheme to periodically carry out a health assessment check to identity those at most risk of developing chronic illnesses.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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