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- Kosuke Matsumori, Kazuki Hamada, Keiji Oishi, Masatoshi Okimura, Kosei Yonezawa, Michiya Watanabe, Yukari Hisamoto, Keita Murakawa, Ayumi Fukatsu-Chikumoto, Kazuki Matsuda, Syuichiro Ohata, Ryo Suetake, Toshiaki Utsunomiya, Yoriyuki Murata, Yoshikazu Yamaji, Maki Asami-Noyama, Nobutaka Edakuni, Tomoyuki Kakugawa, Tsunahiko Hirano, and Kazuto Matsunaga.
- Yamaguchi-Ube Medical Center, Japan.
- Intern. Med. 2024 Aug 15; 63 (16): 231723202317-2320.
AbstractAlthough endoscopic sinus surgery (ESS) is beneficial in improving asthma symptoms, its impact on the lung function in patients with asthma and chronic rhinosinusitis remains unclear. We herein report a case of severe asthma with eosinophilic chronic rhinosinusitis, in which ESS substantially improved airflow limitation and concomitantly reduced fractional exhaled nitric oxide and blood eosinophil counts. ESS likely relieved airflow limitation by suppressing type 2 inflammatory pathways. This case highlights ESS as a promising strategy for achieving clinical remission in patients with severe asthma and chronic rhinosinusitis.
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