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- Mahin Nomali, Mohammad Eghbal Heidari, Aryan Ayati, Amirhossein Tayebi, Oksana Shevchuk, Ramin Mohammadrezaei, Hossein Navid, Sayyed Saeid Khayyatzadeh, Svitlana Palii, Fahimeh Valizade Shiran, Atie Sadat Khorasanian, Zahra Veysi, Atena Jamalzehi, Azadeh Lesani, Golnoosh Assari, Shiva Khani, Kamyab Hassanpour, and Hadis Gerami.
- Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.
- Medicine (Baltimore). 2024 Jan 19; 103 (3): e36804e36804.
BackgroundsOmega-3 supplements are endorsed for heart failure (HF) patients to reduce hospitalizations and mortality, offering anti-inflammatory and cardioprotective benefits.MethodsA comprehensive search was conducted in various databases until November 2022. Eligible studies included clinical trials on patients with HF. Data extraction covered study details, omega-3 specifics, outcomes, and limitations. The JADAD scale was used to assess the risk of bias in randomized controlled trials.ResultsThe review process involved 572 records from database searches, resulting in 19 studies after eliminating duplicates and screening. These studies assessed the impact of omega-3 on various clinical outcomes, such as mortality, hospitalization, cardiac function, and quality of life. Studied duration varied from weeks to years. Omega-3 supplementation demonstrated potential benefits such as improved heart function, reduced inflammation, and decreased risk of cardiovascular events.ConclusionOmega-3 supplementation could benefit heart disease treatment, potentially reducing therapy duration and improving outcomes. Starting omega-3 supplementation for HF patients seems favorable.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
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