• Yuanqiang Lai, Minshan Chen, Mingdi Chen, Chunhe Li, Xiaojuan Chen, Yuanzhi Lai, Zhenzhen Zheng, and Riken Chen.
• Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
• Medicine (Baltimore). 2024 Jan 19; 103 (3): e35150e35150.

BackgroundTo explore the role of gender in the incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism.MethodsTwo researchers search the PubMed Database, Embase Database and Cochrane Library Database from their establishment to October 2022, using Endnote software for document management and RevMan5.3 software for the meta-analysis of the included literature. A total of 11 studies are selected, including 5788 acute pulmonary embolism events and 391 patients (179 males and 212 females) with chronic thromboembolic pulmonary hypertension (CTEPH) under the stated conditions. The results show that there is no statistically significant difference in the incidence of CTEPH between males and females after PE (P = .28), with combined OR of 0.89 and 95% CI 0.72-1.10.Results And ConclusionsGender is found to be absent as a factor in the incidence of CTEPH after acute pulmonary embolism. This may indicate that gender is not a risk factor for CTEPH and that female patients are not necessarily more likely to have a higher incidence than male patients. As such, accurate judgments should be made on the possible complications of all patients after acute pulmonary embolism, which will be conducive to early detection and intervention in the treatment of CTEPH.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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