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- Shinya Maekawa, Shinichi Takano, and Nobuyuki Enomoto.
- Department of Gastroenterology and Hepatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan. Electronic address: maekawa@yamanashi.ac.jp.
- J Formos Med Assoc. 2024 Nov 1; 123 (11): 112411301124-1130.
AbstractThe advent of direct-acting antiviral (DAA) therapy has revolutionized hepatitis C virus (HCV) treatment, enabling most HCV-infected patients to achieve a sustained viral response (SVR) easily and safely in a short period. On the other hand, it is gradually being recognized that a significant proportion of patients are still at risk of developing de novo and recurrent hepatocellular carcinoma (HCC), even after HCV elimination, and therefore, elucidation of the risk of de novo and recurrent HCC, investigation of its molecular basis, and construction of accurate prediction models are emerging as new important clinical topics. In this review, we present recent advances regarding these issues.Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.
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