• Li Wang, Qi-Hui Wen, Li-Juan Wen, Jia-Min Qin, Chun-Mei Ren, and Li-Ming Wen.
• Department of Gastroenterology, Sichuan Mianyang 404 Hospital, Mianyang, Sichuan, 621000, China.
• BMC Anesthesiol. 2024 Jan 22; 24 (1): 3434.

BackgroundDyclonine hydrochloride mucilage is a topical anaesthetic formulated for mucosal surfaces. It is employed frequently for topical anaesthesia of the pharynx prior to endoscopic examinations such as electronic gastroscopy, and few adverse reactions have been reported. This article describes a patient who experienced a transient but severe disturbance of consciousness following oral dyclonine hydrochloride mucilage administration.Case PresentationA 75-year-old female presenting with gastrointestinal bleeding was examined by electronic gastroscopy. Six minutes after oral dyclonine hydrochloride mucilage administration, the patient entered a comatose-like state accompanied by loss of limb muscle tone and profuse perspiration. This response was not accompanied by changes in cardiac rhythm, blood pressure, or respiration rate, suggesting an effect on higher brain centres. After ten minutes, the patient's symptoms were alleviated.ConclusionWe suggest that sites of dyclonine hydrochloride mucilage use be equipped with appropriate rescue devices for these rare events.© 2024. The Author(s).

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