• Georgios Geropoulos, Stavros Moschonas, Georgios Fanariotis, Aggeliki Koltsida, Nikolaos Madouros, Evgenia Koumadoraki, Kontantinos Katsikas Triantafyllidis, Konstantinos S Kechagias, Georgios Koimtzis, Dimitrios Giannis, Athanasios Notopoulos, Efstathios T Pavlidis, and Kyriakos Psarras.
• Second Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
• Medicina (Kaunas). 2023 Dec 24; 60 (1).

AbstractBackground and Objectives: The coronavirus disease-2019 (COVID-19) pandemic influenced the healthcare system tremendously, as well as the number of elective surgical procedures worldwide. The aim of this study is to investigate the COVID-19 pandemic's impact on esophagectomies. Materials and Methods: The MEDLINE (via PubMed), Cochrane Library, and Google Scholar bibliographical databases were systematically searched. Original clinical studies investigating the outcomes of esophageal cancer surgery during the COVID-19 pandemic were deemed eligible. After exclusion criteria were applied, eight studies were considered eligible for inclusion. Results: Eight studies with non-overlapping populations, reporting on patients undergoing esophagectomy for resectable esophageal cancer during the COVID-19 pandemic, were included in our analysis, with a total of 18548 patients. Background characteristics for age, lung disease, smoking history as well as Body Mass Index and age were equal among the groups. The background of diabetes presented a statistically significant difference among the groups. Perioperative outcomes like reoperation rates, the length of intensive care unit stay, or readmission rates were not significantly increased during the pandemic. The 30-day readmission, and 30- and 90-day mortality were not affected either. The length of hospital stay was significantly lower in the non-pandemic period. Conclusions: The results of our study support the evidence that in the context of the COVID-19 pandemic, esophageal cancer operations took place safely and effectively, similarly to the standards of the non-COVID-19 era.

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