• Anamá Di Prinzio, Ana C Torre, Susana E Perez Rios, and Luis D Mazzuoccolo.
• Servicio de Dermatología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. E-mail: anama.diprinzio@hospitalitaliano.org.ar.
• Medicina (B Aires). 2024 Jan 1; 84 (1): 163167163-167.

AbstractBazex syndrome is a paraneoplastic disorder most commonly linked to squamous cell carcinomas of the upper aerodigestive tract, followed by lung cancer and other malignancies. It manifests through three stages of skin involvement that mirror the tumor's progression. Remarkably, skin lesions precede tumor symptoms or diagnosis in two-thirds of cases, underscoring the crucial role of suspecting this condition as it can promptly reveal an underlying neoplasm. Treatment primarily focuses on addressing the root neoplasm, with recurrent skin lesions potentially indicating tumor relapse. In this context, we present a clinical case involving a male patient whose manifestation of this syndrome facilitated the timely diagnosis of lung adenocarcinoma. This case underscores the significance of understanding this uncommon syndrome and its link to cancer, enabling early and accurate oncological diagnosis.

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