• Laxman Mandal, Garima Rijal, Raj Singh, Bhawana Tiwari, Farhat Jahan, Dipti Lama, Sagun Shrestha, Ram Narayan Kurmi, and Uma Das.
• Department of Internal Medicine, Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal.
• JNMA J Nepal Med Assoc. 2023 Sep 1; 61 (265): 691694691-694.

IntroductionSepsis is a life-threatening dysfunction and is one of the common causes of admission in intensive care units. Early diagnosis and management improves the outcome of patients. The aim of this study was to find out the prevalence of sepsis among patients admitted to the intensive care unit of a tertiary care centre.MethodsA descriptive cross-sectional study was conducted among patients admitted to the intensive care unit of a tertiary care centre after obtaining ethical approval from the Institutional Review Committee. Data of patients admitted from 1 February 2022 to 31 January 2023 was collected between 6 April 2023 to 27 April 2023. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.ResultsAmong 1001 patients, the prevalence of sepsis was 278 (27.77%) (25-30.54, 95% Confidence Interval). Among them, 209 (75.17%) developed septic shock. The mean age was 56.6±19.34 years. Pneumonia 43 (15.46%) and genitourinary infection 43 (15.46%) were the most common sources of infection and the source was unknown in 124 (44.60%) of patients. Hypertension 75 (26.97%) was the most common comorbidity. Acute kidney injury 166 (59.71%) was the most common complication followed by thrombocytopenia 165 (59.35%) and transaminitis 79 (28.41%).ConclusionsThe prevalence of sepsis among patients admitted to the intensive care unit was higher than other studies done in similar settings.Keywordsinfection; intensive care unit; sepsis; tertiary care centre.

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