• Rashmi Thapa, Mohir Pokharel, Saroj Paudel, Tunam Khadka, Priyanka Sapkota, Rohit Rana, Moneec Pokharel, and Dinesh Chhetri.
• Department of Emergency Medicine, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2023 Aug 1; 61 (264): 636638636-638.

IntroductionAcid peptic disease is caused by excessive acid secretion or weakened mucosal defense. Symptoms include epigastric pain, bloating, and nausea. Factors like gastric acid, Helicobacter pylori infection, alcohol consumption, smoking, and stress contribute to peptic ulcers. Imbalances between offensive and defensive factors can lead to ulcers. Acid-related disorders impact the quality of life and mortality. Accurate diagnosis and prompt treatment are vital. This study aimed to find out the prevalence of acid peptic disease among patients with acute abdomen in the Department of Emergency Medicine in a tertiary care centre.MethodsA descriptive cross-sectional study was conducted from 2 April 2022 and 2 April 2023 among the patients presented in the Department of Emergency Medicine in a tertiary care centre. Ethical approval was obtained from the Institutional Review Committee. All patients presenting with acute abdominal pain in the Emergency Department were included in the study. Patients not giving consent were excluded from the study. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.ResultsOut of the 400 patients with acute abdomen, the prevalence of acid peptic disease was found to be 87 (21.75%) (17.71-25.79, 95% Confidence Interval).ConclusionsThe prevalence of acid peptic disease among patients with acute abdomen was found to be lower than in other studies performed in similar settings.Keywordsacute abdomen; gastroenteritis; Helicobacter pylori; peptic ulcer.

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