• Fereshteh Ghadiri, Mohammad Ali Sahraian, Fereshteh Ashtari, Seyed Mohammad Baghbanian, Nastaran Majdi-Nasab, Hamidreza Hatamian, Fardin Faraji, Asghar Bayati, Ehsan Sharifipour, Nazanin Jalali, Hossein Mozhdehipanah, Hoda Kamali, Saeideh Ayoubi, Sharareh Eskandarieh, and Naser MoghadasiAbdorrezaA0000-0002-8598-0911Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran..
• Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
• Arch Iran Med. 2023 Aug 1; 26 (8): 413418413-418.

BackgroundMultiple sclerosis (MS) may be affected by socioeconomic status (SES). This study aims to explore the determinants of SES among Iranian patients with MS and examine how these factors relate to disability and disease progression.MethodsAll patients with MS listed in the nationwide MS registry of Iran (NMSRI) until January 8, 2022, were included in this population-based study.ResultsAmong the 5153 patients, most were female (74.5%), married (70.8%), and did not hold an academic degree (53.8%). Unemployment (OR: 3.75) and being unmarried (OR: 2.60) were significantly associated with Expanded Disability Status Scale (EDSS)≥6, and the time to progression was shorter in the unemployed group (P value: 0.03). There was also a significant negative correlation between the time to progression and the age at disease onset.ConclusionThe study suggests that providing financial and social support to MS patients and their families through investment could reduce both individual and societal burdens.© 2023 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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