• Medicine · Feb 2024

    Review

    Prospect of research on anti-atherosclerosis effect of main components of traditional Chinese medicine Yiqi Huoxue Huatan recipe through gut microbiota: A review.

    • Hongtao Huang, Hanjun Zhao, Lv Wenqing, Feiyue Xu, Xiaolong Wang, Yili Yao, and Yu Huang.
    • Department of Cardiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai, China.
    • Medicine (Baltimore). 2024 Feb 2; 103 (5): e37104e37104.

    AbstractThe incidence and mortality rates of cardiovascular diseases are on the rise globally, posing a severe threat to human health. Atherosclerosis (AS) is considered a multi-factorial inflammatory disease and the main pathological basis of cardiovascular and cerebrovascular diseases, as well as the leading cause of death. Dysbiosis of the gut microbiota can induce and exacerbate inflammatory reactions, accelerate metabolic disorders and immune function decline, and affect the progression and prognosis of AS-related diseases. The Chinese herbal medicine clinicians frequently utilize Yiqi Huoxue Huatan recipe, an effective therapeutic approach for the management of AS. This article reviews the correlation between the main components of Yiqi Huoxue Huatan recipe and the gut microbiota and AS to provide new directions and a theoretical basis for the prevention and treatment of AS.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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