• Muhammet Hamza Halil Toprak, Kahraman Yakut, Nurullah Yilmaz, Berra Zumrut Tan Recep, Behzat Tüzün, Erkut Ozturk, İsa Ozyilmaz, Ali Can Hatemi, and İbrahim Cansaran Tanidir.
• Department of Pediatric Cardiology, Saglik Bilimleri University, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
• Medicine (Baltimore). 2024 Feb 2; 103 (5): e37121e37121.

AbstractThis study aims to share the results of critically ill newborn cases with interrupted aortic arch (IAA) and Left ventricular outflow tract (LVOT) obstruction (LVOTO) who underwent the hybrid approach, which consists of bilateral pulmonary artery banding and/or patent ductus arteriosus stenting, as first-line treatment. This retrospective study includes the results of high-risk term newborns whom we applied a hybrid approach due to IAA and LVOTO in our clinic between January 1, 2021 and December 31, 2021. The demographic characteristics, hybrid approach methods and results of the cases were evaluated. Nine cases underwent hybrid approach during the study period. The mean age and weight at interventions were 7 days (3-16 days) and 3280 g (2700-4300 g). Six of the patients were diagnosed with type B IAA, 2 with type A, and one with type C. LVOTO was present in 7 patients. The success rate for the procedures was 100%. No patients died during the procedure or within the first 5 days after the procedure or from reasons related to the procedure. The median length of the hospital stay after stent placement was 28 days (22-35 days) for discharged patients. Three patients died in interstage period, and 6 patients underwent total corrective surgery after a median of 7 months (4-10 months). The average LVOT diameter was increased from 3.1 mm to 4.8 mm before total repair surgery. The hybrid approach should be kept in mind for treating high risk newborns with IAA with LVOTO and high-risk newborns who are not suitable for single stage total corrective surgery.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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