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Case Reports
Successful Treatment of Malignant Lymphoma Following Transcatheter Aortic Valve Replacement: A Case Report.
- Takumi Osawa, Kazuko Tajiri, Tomoya Hoshi, Masaki Ieda, and Tomoko Ishizu.
- Department of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
- Intern. Med. 2024 Sep 1; 63 (17): 243324372433-2437.
AbstractA 67-year-old woman with severe aortic stenosis (AS) was transferred to our hospital for large B-cell lymphoma treatment. Because of her high risk of anthracycline-induced cardiotoxicity due to severe AS and low performance status, the patient was initially treated with doxorubicin-free chemotherapy. However, doxorubicin was considered necessary to achieve complete remission. After multidisciplinary team discussions, transcatheter aortic valve replacement (TAVR) was performed without complications. Nine days after TAVR, the patient received the first cycle of anthracycline-containing chemotherapy (R-CHOP). Currently, 12 months after completing 4 cycles of R-CHOP, the patient remains in complete remission without having developed cardiotoxicity.
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