• Internal medicine · Sep 2024

    Review Case Reports

    Pancreatic Neuroendocrine Neoplasm Concomitant with Branch-duct Intraductal Papillary Mucinous Neoplasm: A Case Report and Literature Review.

    • Yugo Sawai, Masanori Asada, and Hiroyuki Marusawa.
    • Department of Gastroenterology and Hepatology, Japanese Red Cross Osaka Hospital, Japan.
    • Intern. Med. 2024 Sep 1; 63 (17): 242724322427-2432.

    AbstractReports of pancreatic neuroendocrine neoplasm (P-NEN) concomitant with intraductal papillary mucinous neoplasm (IPMN) are gradually increasing. However, many of these cases were diagnosed in the resected specimen incidentally. We herein report a case of minimal P-NEN concomitant with branch-duct IPMN that was successfully diagnosed preoperatively by contrast-enhanced endoscopic ultrasonography (EUS) and an EUS-guided fine-needle biopsy. These findings suggest that P-NEN as well as pancreatic ductal adenocarcinoma should be considered as concurrent tumors developing in patients with IPMNs. EUS is an essential modality when evaluating IPMN for detecting small lesions concomitant with IPMN.

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