• Jorge B A Seixas, Giovanni LuzKleberKDepartamento de Infectologia. Instituto de Medicina Tropical da Universidade Federal do Rio Grande do Norte. Hospital Giselda Trigueiro. Rio Grande do Norte. Portugal., and Vitor Pinto Junior.
• Unidade de Ensino e Investigação de Clínica Tropical. Instituto de Higiene e Medicina Tropical. Universidade NOVA de Lisboa. Lisboa. Portugal.
• Acta Medica Port. 2024 Feb 1; 37 (2): 126135126-135.

AbstractDengue is a vector-borne disease that has a significant impact on global public health. The vector mosquito belongs to the genus Aedes. Two species play a key role in human transmission: Ae. aegypti, which has adapted to the urban environment of highly populated areas in tropical and subtropical countries, leading to a dramatic increase in dengue cases over the years, and Ae. albopictus, which poses a potential threat to temperate climate countries due to its ability to adapt to colder climates. The disease is widespread across the world, posing a risk to nearly half of the world's population. Although most cases are asymptomatic, dengue causes a burden on healthcare systems and mainly affects the younger population. The disease is also spreading to temperate climate countries, thus becoming a global threat. Vector control measures and vaccine development have been the main prevention strategies, as there is still no effective treatment for the disease.

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