• D Keegan Stombaugh, Karen Singh, Amir Malek, Amanda Kleiman, Susan Walters, Akram Zaaqoq, Michelle Dawson, John Steven McNeil, John Kern, and Michael Mazzeffi.
• University of Virginia, Department of Anesthesiology, Charlottesville, VA.
• J. Cardiothorac. Vasc. Anesth. 2024 Apr 1; 38 (4): 957963957-963.

ObjectivesChronic alcohol use is associated with chronic pain and increased opioid consumption. The association between chronic alcohol use and acute postoperative pain has been studied minimally. The authors' objective was to explore the association among preoperative alcohol use, postoperative pain, and opioid consumption after coronary artery bypass grafting (CABG).DesignA retrospective cohort study.SettingAt a single academic medical center.ParticipantsPatients having isolated CABG.InterventionsNone.Measurements And Main ResultsDemographics, comorbidities, and baseline alcohol consumption were recorded. Primary outcomes were mean pain score and morphine milligram equivalent (MME) consumption on postoperative day 0. Among 1,338 patients, there were 764 (57.1%) who had no weekly preoperative alcohol use, 294 (22.0%) who drank ≤1 drink per week, 170 (12.7%) who drank 2-to-7 drinks per week, and 110 (8.2%) who drank 8 or more drinks per week. There was no significant difference in mean pain score on postoperative day 0 in patients who consumed different amounts of alcohol (no alcohol = 5.3 ± 2.2, ≤1 drink = 5.2 ± 2.1, 2 to 7 drinks = 5.3 ± 2.3, 8 or more drinks = 5.4 ± 1.9, p = 0.66). There was also no significant difference in median MME use on postoperative day 0 in patients who consumed different amounts of alcohol (no alcohol = 22.5 mg, ≤1 drink = 21.1 mg, 2-to-7 drinks = 24.8 mg, 8 or more drinks = 24.5 mg, p = 0.14).ConclusionsThere is no apparent association among mild-to-moderate preoperative alcohol consumption and early postoperative pain and opioid use in patients who underwent CABG.Copyright © 2024 Elsevier Inc. All rights reserved.

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