• J M Akerele, C Erameh, A A Okomayin, A Dongo, F Omosofe, G Ikponmonsa, K O Osemobor, N N Akerele, and S Ngwu.
• Department of Surgery, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.
• Niger J Clin Pract. 2024 Jan 1; 27 (1): 148152148-152.

AbstractMyasthenia gravis (MG) is an antibody-mediated autoimmune disease with the cardinal feature being exertional voluntary skeletal muscle weakness and fatigability. It can be an isolated finding or in association with other autoimmune conditions such as Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE), or rheumatoid arthritis. Thymectomy is recommended for most patients with MG whose symptoms begin before the age of 60 years. Patients with thymoma or thymic hyperplasia do respond to thymectomy compared to those without thymoma or enlarged thymus. Those with enlarged goiter would benefit from thyroidectomy. The management of these patients requires a multidisciplinary approach as performed in a low-resource setting. We are reporting the case of a 24-year-old who presented with MG with toxic goiter and had good control on medication. A computed tomography scan of the chest showed a superior mediastinal mass and a soft tissue scan of the neck was done which showed a diffusely enlarged thyroid gland. She subsequently had thymectomy and subtotal thyroidectomy with a satisfactory outcome. We highlight this case to show that MG with thymoma and goiter could coexist. Reports of such findings are infrequently reported in our environment.Copyright © 2024 Copyright: © 2024 Nigerian Journal of Clinical Practice.

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