• Internal medicine · Sep 2024

    Case Reports

    The First Case of Mycobacterium interjectum Pulmonary Disease in Japan: A Case Report.

    • Asuka Yamaguchi, Naohisa Urabe, Nozomi Tokita, Masakazu Sasaki, Noboru Iizuka, Susumu Sakamoto, and Kazuma Kishi.
    • Department of Respiratory Medicine, Toho University Omori Medical Center, Japan.
    • Intern. Med. 2024 Sep 1; 63 (17): 246124652461-2465.

    AbstractWe herein report a case of Mycobacterium interjectum pulmonary disease (M. interjectum-PD) that improved considerably after azithromycin (AZM), rifampicin (RFP), and ethambutol (EB) therapy. A 69-year-old woman, managed locally for suspected NTM-PD based on chest computed tomography (CT) findings was referred to our hospital for worsening productive cough six years after the initial diagnosis. High-resolution chest CT showed right middle and left lower lobe bronchiectasis with middle and centrilobular nodules. Bronchial washing and sputum culture yielded M. interjectum. Treatment with AZM, RFP, and EB resulted in sputum culture conversion, and the chest CT findings subsequently improved. This is the first reported case of M. interjectum-PD in Japan.

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