• Peiliang Wu, Cong Wang, Yiran Jiang, Zhi Zhang, Junlan Gao, and Zhe Fan.
• Department of General Surgery, the Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.
• Medicine (Baltimore). 2024 Feb 9; 103 (6): e37193e37193.

RationaleEpidermoid cyst (EC) is a common clinical condition and it can be filled with keratinized material. EC often represents painless, slow progressive growth, and single cyst. The cyst is usually 1 to 5 cm in size. Giant epidermoid cysts on the buttock area are extremely rare, and reports of giant epidermoid double cysts on the buttock are even rarer.Patient ConcernsThis paper reports a patient with a painless mass was on the left buttock.DiagnosisA giant epidermoid double cysts with infection in a left buttock paranal location.InterventionsThe mass was surgically removed.OutcomesThe patient recovered well after surgical treatment and currently has no recurrence.ConclusionFor patients with EC, MRI is recommended as a routine examination before surgery in order to detect the variation and extent of the cyst early. This lays a foundation for the complete resection of the lesion during the operation. The review of relevant literature will hopefully be helpful to clinicians.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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