• Medicine · Feb 2024

    Review Case Reports

    Two successful pregnancies in a membranous nephropathy patient: Case report and literature review.

    • Congcong Qin, Zhijuan Hu, Yanan Shi, Hui Cui, and Jiejie Li.
    • Department of Internal Medicine, Hebei North University, Zhangjiakou, China.
    • Medicine (Baltimore). 2024 Feb 9; 103 (6): e37111e37111.

    BackgroundPregnancy in patients with nephrotic syndrome presents enormous challenges to both the mother and fetus, and there are no treatment guidelines for these patients.MethodsWe show a case of a woman with anti-PLA2R antibody-positive membranous nephropathy who did not have a kidney biopsy. Her clinical course during both pregnancies was closely followed and her medications were guided.ResultsShe gave birth to 2 healthy babies and her condition was very well controlled with the help of medication.ConclusionPatients with nephrotic syndrome can have successful pregnancies after drug treatment. In addition, similar to the non-pregnant population, percutaneous kidney biopsy is not required for the diagnosis of idiopathic membranous nephropathy (IMN) in pregnant nephrotic syndrome patients with anti-PLA2R antibody positive, but the etiology of secondary MN should be excluded.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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