• Cell metabolism · Jun 2016

    Review

    Metformin as a Tool to Target Aging.

    • Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, and Mark A Espeland.
    • Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: nir.barzilai@einstein.yu.edu.
    • Cell Metab. 2016 Jun 14; 23 (6): 106010651060-1065.

    AbstractAging has been targeted by genetic and dietary manipulation and by drugs in order to increase lifespan and health span in numerous models. Metformin, which has demonstrated protective effects against several age-related diseases in humans, will be tested in the TAME (Targeting Aging with Metformin) trial, as the initial step in the development of increasingly effective next-generation drugs.Copyright © 2016. Published by Elsevier Inc.

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    This article appears in the collection: Metformin and anti-aging.

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