• Internal medicine · Sep 2024

    Case Reports

    A Case of Solitary Pure Ground-glass Opacity Suspected of Being the Initial Presentation of Nonfibrotic Hypersensitivity Pneumonitis.

    • Natsushi Kubota, Tsukasa Okamoto, Sho Shimada, Takashi Yamana, Yuki Iijima, Rie Sakakibara, Sho Shibata, Takayuki Honda, Takahiro Mitsumura, Tsuyoshi Shirai, Haruhiko Furusawa, Tomoya Tateishi, Takuya Adachi, Susumu Kirimura, and Yasunari Miyazaki.
    • Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
    • Intern. Med. 2024 Sep 15; 63 (18): 254325462543-2546.

    AbstractWe herein report a rare case of hypersensitivity pneumonitis (HP) that was initially demonstrated as solitary pure ground-glass opacity (GGO) on chest computed tomography (CT). A 51-year-old woman with a history of breast cancer underwent follow-up CT, which revealed solitary pure GGO. The patient developed exertional dyspnea after two years, and CT revealed diffuse centrilobular nodules in addition to GGO, which had increased in size. An antigen avoidance test was performed to diagnose HP, leading to the resolution of CT abnormalities, including the GGO. Our findings suggested that nonfibrotic HP can present as solitary pure GGO.

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