• Internal medicine · May 2024

    Review Case Reports

    New-onset Systemic Lupus Erythematosus Manifestation Following COVID-19: A Case Report and Literature Review.

    • Yuya Sumichika, Jumpei Temmoku, Kenji Saito, Shuhei Yoshida, Haruki Matsumoto, Guy Watanabe, Akihito Utsumi, Yuya Fujita, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, and Kiyoshi Migita.
    • Department of Rheumatology, Fukushima Medical University School of Medicine, Japan.
    • Intern. Med. 2024 May 15; 63 (10): 149114981491-1498.

    AbstractCoronavirus disease 2019 (COVID-19) is a respiratory viral disease, and several cases of autoimmune diseases have been reported after infection. This report presents the case of a 38-year-old Japanese woman who developed systemic lupus erythematosus (SLE) following COVID-19. Clinical manifestations included dermatological complications, joint pain, and positive autoantibodies. The patient met the SLE classification criteria, and renal involvement was observed. Her symptoms improved with immunosuppressive therapy. A literature review identified 10 similar cases, those with lymphopenia and renal involvement. SLE should be considered in patients with persistent nonspecific symptoms after COVID-19 infection, particularly when hematologic and renal involvement are present.

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